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Iressa® Non-Inferior to Taxotere® in Lung Cancer Treatment
Lung cancer patients who took AstraZenca’s Iressa drug lived about as long as those taking Sanofi-Aventis’s toxotere chemotherapy, according to a new study.
AstraZeneca said the late-stage study compared overall survival between Iressa and Taxotere in 1,466 patients with advanced, non-small cell lung cancer who had received previous treatment.
The study showed Iressa was “non-inferior” to Taxotere. The data was presented at the World Conference on Lung Cancer in Korea.
AstraZeneca also said that Iressa had a more favorable “tolerability profile” and “superior quality of life” for patients, versus Taxotere.
Iressa is a type of targeted therapy known as an epidermal growth factor receptor tyrosine kinase inhibitor.
A study in 2004 showed that Iressa failed to extend lives in lung cancer patients. The U.S. Food and Drug Administration then restricted use of the drug.
AstraZeneca is sharing the latest data with the regulatory agencies.
For more information on Iressa and Taxotere or to seek help in obtaining your treatment, go to www.cancerrxassist.com or call (866)845-8668
Golimumab Application Filed with the FDA
Centecor, Inc filed an application with the U.S. Food and Drug Administration (FDA) requesting approval for Golimumab, a treatment for adults living with psoriatic arthritis, rheumatoid arthritis and ankylosing spondylitis.
Golimumab is a human monclonol antibody that targets and inactivates tumer necrosis factor alpha—a signaling protein that plays an important role in many immune-mediated disease, including psoriatic arthritis.
Five Phase 3 trials strongly support that using golimumab helps improve the signs and symptoms of arthritis, psoriatic arthritis and ankylosing spondylitis. In the studies, the drug was administered as a monthly injection.
“Based on the magnitude of the response reported in the recent clinical trials, I would not be surprised if the FDA votes to approve Centocor’s application,” said Bruce Bebo, Jr. PhD, Director of research for the National Psoriasis Foundation.
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